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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDR2
All Species:
33.94
Human Site:
Y825
Identified Species:
57.44
UniProt:
Q16832
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16832
NP_001014796.1
855
96736
Y825
A
I
C
P
D
S
V
Y
K
L
M
L
S
C
W
Chimpanzee
Pan troglodytes
Q7YR43
909
100624
Y877
P
A
C
P
Q
G
L
Y
E
L
M
L
R
C
W
Rhesus Macaque
Macaca mulatta
XP_001118206
855
96702
Y825
A
I
C
P
D
S
V
Y
K
L
M
L
S
C
W
Dog
Lupus familis
XP_536144
849
95798
Y819
V
I
C
P
D
S
V
Y
K
L
M
L
S
C
W
Cat
Felis silvestris
Mouse
Mus musculus
Q62371
854
96464
Y824
A
L
C
P
D
S
V
Y
K
L
M
L
S
C
W
Rat
Rattus norvegicus
Q63474
910
101146
Y878
P
A
C
P
Q
T
L
Y
E
L
M
L
R
C
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515915
914
101965
Y883
A
I
C
P
D
P
V
Y
K
L
M
L
S
C
W
Chicken
Gallus gallus
Q91987
818
91718
Q787
D
L
M
L
G
C
W
Q
R
E
P
H
M
R
L
Frog
Xenopus laevis
O73798
1358
153845
Q1246
E
L
M
R
M
C
W
Q
F
N
P
K
M
R
P
Zebra Danio
Brachydanio rerio
XP_684261
892
101731
Y863
P
M
C
P
D
P
V
Y
K
L
M
L
S
C
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
T662
E
Q
S
V
K
R
P
T
F
T
D
I
S
N
R
Honey Bee
Apis mellifera
XP_392450
898
100991
Y863
T
M
C
P
E
E
V
Y
R
M
M
C
S
C
W
Nematode Worm
Caenorhab. elegans
NP_508572
797
90284
Y760
R
M
C
P
S
K
L
Y
N
E
Q
I
L
P
C
Sea Urchin
Strong. purpuratus
XP_001202828
913
103393
H876
P
Q
C
P
K
D
I
H
N
L
M
K
R
C
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
99.3
96.4
N.A.
95.9
52.8
N.A.
80.1
27.1
21
74.5
N.A.
24.3
30.2
32.8
39.8
Protein Similarity:
100
66
99.5
97.8
N.A.
97.3
66.1
N.A.
85.8
42.8
34.3
82.6
N.A.
41.9
48.7
52
55
P-Site Identity:
100
53.3
100
93.3
N.A.
93.3
53.3
N.A.
93.3
0
0
80
N.A.
6.6
53.3
20
40
P-Site Similarity:
100
66.6
100
93.3
N.A.
100
73.3
N.A.
93.3
13.3
6.6
86.6
N.A.
13.3
80
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
79
0
0
15
0
0
0
0
0
8
0
72
8
% C
% Asp:
8
0
0
0
43
8
0
0
0
0
8
0
0
0
0
% D
% Glu:
15
0
0
0
8
8
0
0
15
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
0
29
0
0
0
0
8
0
0
0
0
15
0
0
0
% I
% Lys:
0
0
0
0
15
8
0
0
43
0
0
15
0
0
0
% K
% Leu:
0
22
0
8
0
0
22
0
0
65
0
58
8
0
8
% L
% Met:
0
22
15
0
8
0
0
0
0
8
72
0
15
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
15
8
0
0
0
8
0
% N
% Pro:
29
0
0
79
0
15
8
0
0
0
15
0
0
8
8
% P
% Gln:
0
15
0
0
15
0
0
15
0
0
8
0
0
0
0
% Q
% Arg:
8
0
0
8
0
8
0
0
15
0
0
0
22
15
8
% R
% Ser:
0
0
8
0
8
29
0
0
0
0
0
0
58
0
0
% S
% Thr:
8
0
0
0
0
8
0
8
0
8
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
50
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
72
% W
% Tyr:
0
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _